A Frenchman who suffered a severe heart attack has apparently spontaneously awakened after 1 1/2 hours without a normal heartbeat (but mechanical heart message). From the story:

A man whose heart had stopped beating woke up just as surgeons were about to remove his organs for donation, it was disclosed yesterday.

Doctors in Paris earlier this year called in transplant surgeons after failing to resuscitate a 45-year old man believed to have suffered a massive heart attack in the French capital. According to a report by the Paris university hospital’s ethics committee–seen by Le Monde newspaper–doctors continued providing a heart massage for an hour and a half while they waited for the surgeons to arrive.

When the surgeons began operating on the man to remove his organs, he began to breathe, his pupils became responsive and he reacted to a pain test.

As soon as I read that I thought this could materially impact the ethics of non heart beating cadaver donor protocols that start procuring organs five minutes after cardiac arrest. I am not alone:

In particular, the case is likely to ignite public debate over so-called controlled non-heart-beating organ donation (NHBOD)–retrieving organs when the heart stops, which has only been legal in France since last year. Before then a patient had to be declared brain dead before transplant could occur. NHBOD is legal in the UK.

< "All specialised medical literature on the subjects allows one to conclude that a person who has suffered cardiac arrest and has had proper heart massage for over 30 minutes is, for all purposes, brain dead," said Professor Alain Tenaillon, in charge of organ transplants at France's biomedical agency. "But one must acknowledge that exceptions do exist...there are no hard and fast rules on best practice," he told Le Monde.

I am not sure what the answer is. But it seems to me that the public’s confidence in organ donation requires that this matter be looked at closely, as well as trying to determine if there are other such cases.

Researchers studying embryonic stem cells have explored the first fork in the developmental road, getting a new look at what happens when fertilized eggs differentiate to build either an embryo or a placenta. (ScienceDaily)

An FDA advisory panel on Monday voiced concern over the potential risks of conducting early HIV vaccine trials among teenagers in the U.S., Bloomberg reports. According to the panel, although such trials are justified in countries where HIV/AIDS is spreading more quickly, the risks might not outweigh the benefits in the U.S. (News-Medical)

Embryo chromosome screening should not be offered to women to improve their chances of an IVF baby, expert guidelines say.

The British Fertility Society says there is no evidence it improves the chance of success, or cuts the risk of miscarriage for older women. (BBC)

US stem-cell researchers are calling for changes to state laws that prohibit compensating women who donate eggs for research. The laws, in leading stem-cell research states such as Massachusetts and California, are crippling the promising field of ‘therapeutic cloning’ that could produce useful embryonic stem-cell lines for studying various human diseases, they say. (Nature)

France may have to reconsider its medical definition of death after a heart-attack victim came alive in the operating theatre as doctors were about to remove his organs for transplant. (The Independent)