Chronic Pain: The Long Road to Discovery

March 28, 2023

(Nature) – The picture that emerged was complex and surprising. Over the past few decades, a growing body of evidence has indicated that the very machinery that processes pain can help to sustain the sensation or make it worse. Some researchers have explored unexpected interactions between the immune and nervous systems, showing, for instance, that inflammation, long considered a provocateur of pain, might also be crucial for resolving it. Others have shown how depression, anxiety and other kinds of emotional distress can both feed — and feed off — the experience of pain. (Read More)