The Threat of Fungal Infections Is Growing. Why Is It So Hard to Make New Drugs?

February 12, 2024

Agar plate with bacteria

(NBC News) – Last summer, the Food and Drug Administration denied an application for a new antifungal drug called olorofim, sending it back to the company with a request for more data. If approved, it would have been the first time since the early 2000s that the FDA cleared an antifungal that works in an entirely novel way.

It couldn’t come at a more important time: In recent years, the potential danger fungal infections pose to human health has become more and more apparent, as fungi either evolve to evade treatments or spread beyond their typical geographical regions. Doctors around the world are desperate for new medicines to combat the growing threat. (Read More)