They Thought Ozempic Would Help Them Lose Weight. It Didn’t Work.

April 1, 2024

crowd of people walking on a sidewalk

(Wall Street Journal) – Behind the blockbuster success of drugs like Ozempic and Wegovy is a less-noticed phenomenon: Some people don’t lose much weight on them.

There is wide variation in weight loss on these types of drugs, called GLP-1s. Doctors say roughly 10% to 15% of people who try them are “non-responders,” typically defined as those who lose less than 5% of their body weight. These patients, doctors say, don’t experience enough appetite reduction to result in significant weight loss. (Read More)