April 9, 2020

How Does COVID-19 Kill? Uncertainty Is Hampering Doctor’s Ability to Choose Treatments

(Nature) – How does COVID-19 kill? Uncertainty over whether it is the virus itself — or the response by a person’s immune system — that ultimately overwhelms a patient’s organs, is making it difficult for doctors to determine the best … Read More

April 9, 2020

International Trial Uses AI to Rapidly Identify Optimal Covid-19 Treatments

(STAT News) – A randomized controlled trial ramping up in dozens of hospitals around the world proposes a third way — fusing those two approaches together by using artificial intelligence to home in on the most effective treatments on the … Read More

April 9, 2020

“Human Challenge Trials,” Where Healthy Volunteers Would Be Exposed to Covid-19, Explained

(Vox) – Now, a bioethicist and two epidemiologists are proposing a bolder option: You can volunteer to get infected yourself. In a recent article published in the Journal of Infectious Diseases, bioethicist Nir Eyal and epidemiologists Marc Lipsitch and Peter … Read More

April 8, 2020

Data for Gilead’s Potential Coronavirus Therapy Are Coming Soon. Here’s What You Need to Know.

(STAT News) – This month, the world should get the first results from a clinical trial testing the drug remdesivir against Covid-19. They will get a lot of attention. Remdesivir, made by the California biotech Gilead Sciences, is one of … Read More

April 7, 2020

A New Edition of Journal of Medical Ethics Is Now Available

Journal of Medical Ethics (vol. 45, no. 12, 2019) is available online by subscription only. Articles include: “Evidence First, Practice Second in Arthroscopic Surgery: Use of Placebo Surgery in Randomised Controlled Trial” by Kazuha Kizaki, Lisa J Schwartz, and Olufemi … Read More

April 6, 2020

A Fast-Moving Virus Pits Treating Patients Against Finding a Cure

(Bloomberg) – Pharmaceutical-research experts are raising concerns that attempts to offer desperate coronavirus patients some form of treatment may hobble crucial studies of which drugs actually work and which ones don’t. More than 100 off-the-shelf and experimental therapies are being … Read More