Insights into Neural Stem Cells May Point Way to New Tx

November 17, 2014

(MedPage Today) – New insights into how molecular time signaling controls stem cells at different stages of brain development could have implications for the development of novel treatments for psychiatric and neurodegenerative diseases, researchers reported. Researchers from Karolinska Institute, in Stockholm, discovered that TGF-beta acts as a switch-signal in temporal patterning of the vertebrate brain that executes the transition between early and late phases of neurogenesis.