New Clues to Cause of Birth Defects in Children from Older Mothers

February 19, 2015

(Science Daily) – Researchers at Albert Einstein College of Medicine of Yeshiva University have found a possible clue to why older mothers face a higher risk for having babies born with conditions such as Down syndrome that are characterized by abnormal chromosome numbers. Using data from more than 4,000 families obtained in collaboration with the direct-to-consumer genetic testing company 23andMe, Inc., the study showed that the normal process by which parental chromosomes are shuffled before being passed to children appears to be less regulated in older mothers.

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