Study Proposes New Therapy to Suppress Opioid Tolerance

February 20, 2015

(Forbes) – A rising tolerance level is a prescription opioid abuser’s worst enemy. Regular usage of opioids increases a patient’s tolerance level to a point where dosage amounts ride alongside it. The need for new ways to suppress tolerance levels is evident. A new report believes a particular compound could be to blame for the development of opioid tolerance. The study, published in Anesthesiology, the official medical journal of the American Society of Anesthesiologists (ASA), found that CXCL1, a protein produced by spinal cord tissue, plays a significant role in the process.