Twin Copies of Gene Pair Up in Embryonic Stem Cells at Critical Moment in Differentiation

March 6, 2015

(Physorg) – In work published today in Cell Stem Cell a team of researchers led by Professor David L. Spector at Cold Spring Harbor Laboratory (CSHL) showed that the two alleles of Oct4, a gene important in embryonic stem cells, did not come together randomly, at any time or place, but did so at the developmental point at which stem cells begin their maturation into specific cell types.