Zika Highlights Role of Controversial Fetal-Tissue Research
March 31, 2016
(Nature) – A protein that helps Zika virus infect adult skin cells might also give the virus access to stem cells that make brain cells, suggests a study carried out on donated human fetal tissue. The result — published today in Cell Stem Cell — is part of a growing body of research that seeks to determine how Zika might cause birth defects, but that requires a type of tissue that is increasingly controversial for researchers in the United States. Recent advances in neuroscience and cell technology have given hints as to why some babies born to Zika-infected mothers have abnormally small heads — a condition called microcephaly — and other problems, such as eye damage. But to fully understand what is happening in the womb, some scientists say that they need to study tissue from fetuses, which can be donated by couples who terminate pregnancies.