Despite the Hype over Gene Therapy, Few Drugs Are Close to Approval

September 29, 2016

(MIT Technology Review) – Most experts in the medical field will tell you that gene therapy has finally come of age, but the numbers tell a different story. Despite 30 years of research and a bigger pipeline than ever, only a small number of gene therapy trials have completed late-stage testing or are currently in late-stage trials. The concept of gene therapy—replacing or adding a gene to correct a faulty, disease-causing one—was first tested in a clinical trial in 1990. That ushered in a period of enormous hype, with news headlines proclaiming a life-saving approach.