The Interactome of Infected Neural Cells Reveals New Therapeutic Targets for Zika
January 24, 2017
(Medical Xpress) – Zika virus (ZIKV) interferes with the cellular machinery controlling cell division and alters the expression of hundreds of genes guiding the formation and development of neurons and astrocytes, according to findings released on January 23rd 2017 at Scientific Reports. Several evidences indicate that ZIKV infection is associated with microcephaly—a condition in which baby’s head is abnormally small, often because the brain has not developed properly—and other fetal brain defects. Despite the association, cellular alterations caused by the virus are largely unknown.