Genetics of Both Virus and Patient Work Together to Influence the Course of HIV Infection

February 10, 2017

(Eurekalert) – Viral and human genetics together account for about one third of the differences in disease progression rates seen among people infected with the human immunodeficiency virus (HIV), according to new research published in PLOS Computational Biology. The findings suggest that patient genetics influences disease progression by triggering mutations in the HIV viral genome. People with HIV experience different rates of disease progression. HIV progresses faster in people with a higher viral load–the amount of genetic material from the HIV virus found in an infected person’s blood.