How an Outsider in Alzheimer’s Research Bucked the Prevailing Theory–And Clawed for Validation

November 1, 2018

(STAT News) – Armed with the new data, Moir earlier this year tried one more time for an NIH grant, to study in greater detail how herpes viruses might spur Alzheimer’s and, if so, what therapies might work. If he and other scientists are right that beta-amyloid is an antimicrobial, that the brain goes on an amyloid-making immune rampage in response to pathogens, and that the rampage ignites neuron-killing inflammation, it suggests very different therapeutic approaches than the 30-year pursuit of amyloid destroyers.

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