Second Example Reported of a Stem-Cell Transplant in the Clinic Leading to HIV Remission

April 2, 2019

(Nature) – HIV infects immune cells, and the current standard treatment is long-term use of antiretroviral drugs. This keeps virus levels low in the bloodstream but doesn’t eradicate HIV from cells in the body. In 2009, it was reported1 that a person with HIV (commonly referred to as the Berlin patient) who was treated for cancer using a stem-cell transplant subsequently went into viral remission — the virus became undetectable in their body, even in the absence of antiretroviral therapy. No other cases of long-term HIV remission occurring in this way had been recorded since then. But now, writing in Nature, Gupta et al. report a person who has achieved HIV remission for at least 18 months.