A Tiny, 25-Year-Old Study Still Drives Opinion on Pregnancy and Pot

September 3, 2019

(The Atlantic) – Tetrahydrocannabinol, or THC, the main psychoactive molecule in cannabis, is small and fat-soluble, easily crossing the placenta into the fetal bloodstream. The blood circulates THC throughout the body, including the brain, where the molecule can interact with endocannabinoid receptors active in neurodevelopment. How that might affect a developing fetus isn’t easy to sort out, and medical groups acknowledge that the science has limitations and inconsistencies. Still, they say, there are enough studies—many more recent than Dreher’s—linking cannabis use to outcomes such as low birthweight among regular users and changes in brain development to recommend against using it during pregnancy.