Gene Acts as “Master Regulator” of Schizophrenia

September 12, 2019

(Genetic Engineering & Biotechnology News) – Researchers at Children’s Hospital of Philadelphia (CHOP) have identified a gene that acts as a master regulator of schizophrenia during early human brain development, using computational tools designed to investigate gene transcription networks in large collections of brain tissues. The study represented one of the first successful examples of combining computational approaches and stem cell-based experimental models to unravel complex gene networks in psychiatric diseases—and could be applied toward the development of future treatments, CHOP said.