Now in Development: Off-the-Shelf Stem Cells

September 30, 2019

(Knowable Magazine) – Instead, increasingly, labs around the world are seeking to design off-the-shelf cell therapies using universal donor cells that are genetically altered to avoid the many-armed responses of the immune system against foreign tissues. Scientists want to create a suite of such cells tailored for specific tissue repairs: universal muscle cells, universal skin cells or universal insulin-producing pancreatic beta cells. “The big dream is a cell that would be like a pill, which could go into any patient,” says Melton, who called for a global push to realize this vision at a stem cell meeting in Los Angeles in June.