The Dark Side of CRISPR

February 18, 2021

(Scientific American) CRISPR has many functions; one of these is that it can be used to treat disease. Yet the far-reaching, more fraught promise of this technology—one about which scientists seem at once excited and cautious—lies in its ability to eliminate from the gene pool what medical science identifies as faulty or abnormal genes that cause difference in individual people. Certainly, goes the logic of CRISPR’s promise, the goal of ridding future generations of terrible diseases that cause suffering and death and deplete resources, seems an unquestionable enterprise.

But Doudna herself has recognized that CRISPR carries with it “great risk.”