Beyond Gene-Edited Babies: The Possible Paths for Tinkering with Human Evolution

August 22, 2024

A scientist touching a translucent board with a nucleotide

(MIT Technology Review) – Futurists who write about the destiny of humankind have imagined all sorts of changes. We’ll all be given auxiliary chromosomes loaded with genetic goodies, or maybe we’ll march through life as a member of a pod of identical clones. Perhaps sex will become outdated as we reproduce exclusively through our stem cells. Or human colonists on another planet will be isolated so long that they become their own species. The thing about He’s idea, though, is that he drew it from scientific realities close at hand. Just as some gene mutations cause awful, rare diseases, others are being discovered that lend a few people the ability to resist common ones, like diabetes, heart disease, Alzheimer’s—and HIV. Such beneficial, superpower-like traits might spread to the rest of humanity, given enough time. But why wait 100,000 years for natural selection to do its job? For a few hundred dollars in chemicals, you could try to install these changes in an embryo in 10 minutes. That is, in theory, the easiest way to go about making such changes—it’s just one cell to start with. (Read More)