December 14, 2016
(Medical Xpress) – Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, biological pacemaker therapy. Their findings, “Sinoatrial node cardiomyocytes derived from … Read More
December 13, 2016
(The Scientist) – After human somatic cells are reprogrammed into induced pluripotent stem cells (iPSCs), the resulting cells retain both genetic and epigenetic indicators of the age of the person who donated the somatic-cell progenitors, scientists have found. Ali Torkamani, … Read More
December 7, 2016
(Eurekalert) – Researchers at the University of Wisconsin-Madison have developed a novel strategy to reprogram cells from one type to another in a more efficient and less biased manner than previous methods. The ability to convert cells from one type … Read More
December 2, 2016
(NPR) – A nonprofit research group is giving scientists a new way to study the secret lives of human cells. On Wednesday, the Allen Institute for Cell Science provided access to a collection of living stem cells that have been … Read More
November 22, 2016
(Science Daily) – Scientists report in Nature Medicine using human pluripotent stem cells to grow human intestinal tissues that have functioning nerves in a laboratory, and then using these to recreate and study a severe intestinal nerve disorder called Hirschsprung’s … Read More
October 25, 2016
(Eurekalert) – How do you improve a Nobel Prize-winning discovery? Add a debilitating disease-causing gene mutation. In a study published in the journal Proceedings of the National Academy of Sciences, Shinya Yamanaka, MD, PhD, who first created induced pluripotent stem … Read More
October 5, 2016
(Science Daily) – An international collaboration of government, university, and industry resources showed the promise of using RNA as a safe way to both make and modify induced Pluripotent Stem Cells (iPSCs) from patient cells for clinical applications in regenerative … Read More
September 27, 2016
(News-Medical) – Researchers have demonstrated the ability to deliver a fully functional copy of the CLN3 gene to stem cells of patients with juvenile NCL, an inherited neurodegenerative disease in which a mutation in the CLN3 gene causes early-onset severe … Read More
June 20, 2016
(Nature) – Ten years on, the goals have shifted — in part because those therapies have proved challenging to develop. The only clinical trial using iPS cells was halted in 2015 after just one person had received a treatment. But … Read More
June 10, 2016
(PhysOrg) – As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for … Read More
May 11, 2016
(Medical Xpress) – Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes. People with … Read More
May 11, 2016
(UPI) – Induced pluripotent stem cells have allowed scientists to grow mini-organs with the potential to model diseases, test treatments and possibly lead to the growth of whole organs matched to patient’s bodies. New research at the University of Pennsylvania … Read More
May 10, 2016
(New York Times) – The laboratory’s initial breakthrough, published in March with researchers at two other universities, showed that the Zika virus attacked and killed so-called neural progenitor cells, which form early in fetal development and generate neurons in the … Read More
May 2, 2016
(Genetic Engineering & Biotechnology News) – Cellular reprogramming of stem cells derived from one tissue type into a different vastly different tissue typically requires the labor-intensive use of external genes to modify and coax the existing genetic machinery down the … Read More
April 25, 2016
(Nanowerk News) – Scientists at the Gladstone Institutes have invented a new way to create three-dimensional human heart tissue from stem cells (“Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses”). The tissue can be used to model disease … Read More
April 22, 2016
(The Scientist) – Pain can be tough to take, and it’s also difficult to study: rodent models for pain do not necessarily translate to human pain conditions and expression of disease-causing mutations in cell lines may not precisely mimic the … Read More
April 21, 2016
(Medical News Today) – A small minority of patients treated with a common chemotherapy drug develop severe heart damage, but there is currently no way of identifying in advance who they might be. Now, researchers have developed a method using … Read More
April 15, 2016
(Nature) – Induced pluripotent stem cells (iPS) — those derived from adult cells — are inching closer to the clinic. But as a new study helps to show, much work remains before the field can yield mainline treatments. The older … Read More
April 11, 2016
(Medical News Today) – Producing therapeutic stem cells does not lead to genetic changes related to cancer, according to research published in PLoS Genetics. This is encouraging news for those investigating the use of induced pluripotent stem (iPS) cells in … Read More
April 7, 2016
(Medical Xpress) – Therapeutic stem cells can be made without introducing genetic changes that could later lead to cancer, a study in PLOS Genetics has found. The discovery, made by researchers at the Wellcome Trust Sanger Institute, is a boost … Read More
April 5, 2016
(The Conversation) – We often hear about the next big thing in stem cell therapy, though few of these promises eventuate or are backed up by evidence. Well, we think we’re close to a genuine breakthrough in stem cell therapy, … Read More
April 4, 2016
(The Verge) – Researchers have grown a type of complex, hairy skin tissue in the lab for the first time. The fluorescent skin was implanted in living mice, and although its use in humans is a long way off, scientists … Read More
April 4, 2016
(The Guardian) – The result will be easy PGD. A couple who wants children will visit a clinic – he will leave a sperm sample; she will leave a skin sample. A week or two later, the prospective parents will … Read More
March 15, 2016
(Medical News Today) – Researchers in Japan report that neural stem cells derived from readily available T cell-derived iPSCs provide a neurological disease model when cultured in a novel protocol developed by them. The findings are important for the treatment … Read More
March 3, 2016
(San Diego Union-Tribune) – Artificial embryonic stem cells can be safely created for human therapy, according to a study led by a team of San Diego researchers. The study by scientists at The Scripps Research Institute and the J. Craig … Read More
