(MedPage Today) – Absolute risk for nonarteritic anterior ischemic optic neuropathy remained low, however

While rare, NAION is one of the most common causes of acute optic nerve injury in individuals over age 50. It presents as sudden vision loss from lack of blood flow to the optic nerve, earning it the nickname of “optic nerve stroke.”

“The biological mechanism linking GLP-1 receptor agonists to NAION remains unclear, including hypotension, volume depletion from gastrointestinal adverse effects, rapid glycemic improvement with transient microvascular dysregulation, and impaired vascular autoregulation at the optic nerve head,” the researchers added. (Read More)