Biologists Devise Invasion Plan for Mutations

March 23, 2015

(Science) – In the study, published online this week, Gantz and Bier report that the introduced mutation disabled both normal copies of a pigmentation gene on the fruit fly chromosomes, transmitting itself to the next generation with 97% efficiency—a near-complete invasion of the genome. The secret of its success: an increasingly popular gene-editing toolkit called CRISPR, which Gantz and Bier adapted to give the mutation an overwhelming advantage.