New Catalyst Yields More Accurate PSA Test: Peroxidase Mimic Improves Sensitivity of PSA Test 100-Fold

September 18, 2015

(Nanotechnology Now) – Say you’ve been diagnosed with prostate cancer, the second-leading cause of cancer death in men. You opt for surgery to remove your prostate. Three months later, a prostate surface antigen (PSA) test shows no prostate cells in your body. Everyone rejoices. Until 18 months later, when another PSA test reveals that now prostate cells have reappeared. What happened? The first PSA test yielded what’s known as a false negative result. It did not detect the handful of cells that remained after surgery and later multiplied. Now a chemist at Michigan Technological University has made a discovery that could, among other things, slash the numbers of false negatives in PSA tests.