Small-RNA Sequencing of Single Cells

November 3, 2016

(Genetic Engineering & Biotechnology News) – Next-generation sequencing has moved beyond the confines of genomic samples obtained from heterogeneous tissues and begun to disseminate information at the single-cell level. The information gathered from these single-cell genomic methods is becoming increasingly important as researchers dive deeper into various genetic disorders and cancers. Now, investigators at the Karolinska Institute have just published data describing a new method that can measure the absolute numbers of short, noncoding RNA sequences in individual embryonic stem cells. This new approach could improve the understanding of how our genes are regulated and different cell types develop.