New research reveals clues about memory from the brains of ‘SuperAgers’
August 7, 2025

(NBC News) – Gefen and her colleagues at the Mesulam Center have autopsied nearly 80 SuperAger brains and compared them to those of their “neurotypical” peers. They focused on two indicators of Alzheimer’s: protein buildups in the brain called amyloid plaques and tau tangles.
“What we found in memory centers of the SuperAging brain is that there are a lot fewer tau tangles,” Gefen said. “But interestingly, amyloid or plaque pathology doesn’t really differ a whole lot.” (Read More)