May 7, 2014
(Nature) – Four of the six members of a Japanese committee that found misconduct in studies claiming to demonstrate a simple technique to produce stem cells are now facing allegations of irregularities in their own published work. The allegations complicate … Read More
May 7, 2014
(Medical Xpress) – Investigators at the Cedars-Sinai Heart Institute – whose previous research showed that cardiac stem cell therapy reduces scarring and regenerates healthy tissue after a heart attack in humans – have identified components of those stem cells responsible … Read More
May 6, 2014
(Medical Xpress) – Debra Astrug, who once feared she was going blind, can see fine now, thanks to a stem cell transplant she received from her daughter, Jessica. The stem cells came from two pieces of tissue that Dr. Charles … Read More
May 5, 2014
(Science Codex) – During breast-tissue development, a transcription factor called SLUG plays a role in regulating stem cell function and determines whether breast cells will mature into luminal or basal cells. Studying factors, such as SLUG, that regulate stem-cell activity … Read More
May 5, 2014
(Phys.org) – Converting adult cells into stem cells that can develop into other types of specialized cells is one of the most active areas of medical research, holding great promise for the treatment of disease and repair of damaged tissues. … Read More
May 5, 2014
(Medical News Today) – Stem cells are cells that are able to differentiate into specialized cell types, aiding tissue regeneration, cardiovascular disease and blood disease treatments. But now, researchers have found that stem cells from teeth grow to resemble brain … Read More
May 2, 2014
(Medical News Today) – Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation exposure. The … Read More
May 2, 2014
(Eurekalert) – Johns Hopkins researchers say they have successfully used stem cells derived from human body fat to deliver biological treatments directly to the brains of mice with the most common and aggressive form of brain tumor, significantly extending their … Read More
May 2, 2014
(Phys.org) – Stem cells made from the skin of adult, infertile men yield primordial germ cells—cells that normally become sperm—when transplanted into the reproductive system of mice, according to researchers at the Stanford University School of Medicine and Montana State … Read More
May 1, 2014
(Bloomberg) – A scaffold crafted from pig bladder and implanted in patients’ severely injured legs spurred stem cells to make muscle and improve limb function, a method that may change the standard of care. The technique, which didn’t require adding … Read More
April 29, 2014
(Nature) – An analysis of clinical studies that use adult stem cells to treat heart disease has raised questions about the value of a therapy that many consider inappropriately hyped. Early-phase clinical trials have reported that adult stem cells are … Read More
April 29, 2014
(The Wall Street Journal) – A scandal involving Japanese stem-cell research took a surprising turn Monday when the nation’s most revered researcher in the field, Nobel Prize laureate Shinya Yamanaka, apologized for what he described as poor record-keeping. The apology … Read More
April 28, 2014
(Reuters) – BrainStorm Cell Therapeutics said the U.S. Food and Drug Administration approved the start of a mid-stage clinical trial of its adult stem cell treatment for patients with amyotrophic lateral sclerosis (ALS). The Phase II trial will be launched … Read More
April 28, 2014
(Science) – In a bizarre twist to an already very convoluted story, the chair of an investigating committee that found RIKEN stem cell scientist Haruko Obokata guilty of research misconduct is himself now under investigation for alleged research misconduct. He … Read More
April 28, 2014
(News-Medical) – Mass producing human pluripotent stem cells (hPSCs), including embryonic stem cells and induced pluripotent stem cells, for regenerative medicine and drug discovery may have gotten much easier, thanks to a polymer-based 3D culture system developed by Japanese researchers. … Read More
April 28, 2014
(Harvard Stem Cell Institute) – Harvard Stem Cell Institute researchers at Boston Children’s Hospital have reprogrammed mature blood cells from mice into blood-forming hematopoietic stem cells (HSCs) using a cocktail of eight genetic switches called transcription factors. The reprogrammed cells, … Read More
April 28, 2014
(The Japan Times) – A Japanese research team said Friday it has developed a method for mass producing human cells that can develop into other tissue. The team, including Norio Nakatsuji of Kyoto University’s Institute for Integrated Cell-Material Sciences, announced … Read More
April 25, 2014
(BBC) – Skin grown in the laboratory can replace animals in drug and cosmetics testing, UK scientists say. A team led by King’s College London has grown a layer of human skin from stem cells – the master cells of … Read More
April 25, 2014
(Medical News Today) – New research suggests that attempts to isolate an elusive adult stem cell from blood to understand and potentially improve cardiovascular health – a task considered possible but very difficult – might not be necessary. Instead, scientists … Read More
April 24, 2014
(FDA.gov) – Scientists sporting white coats and safety gloves are working in a bright Food and Drug Administration (FDA) lab on an incredible project. They are part of FDA’s MSC Consortium, a large team of FDA scientists studying adult mesenchymal … Read More
April 23, 2014
(Genetic Engineering & Biotechnology News) – Regenerative medicine—the promise of rejuvenating or replacing damaged or diseased tissues—will most likely rely on the use of induced pluripotent stem (iPS) cells, which are obtained when adult cells are essentially thrown into evolutionary … Read More
April 21, 2014
(News-Medical) – The development of stem cell therapies to cure a variety of diseases depends on the ability to characterize stem cell populations based on cell surface markers. Researchers from the Finnish Red Cross have discovered a new marker that … Read More
April 14, 2014
(Bio News Texas) – Neuralstem, a company that specializes in producing commercial quantities of neural stem cells of the brain and spinal cord, publicly presented the findings of their Phase 1 clinical trial involving amyotrophic lateral sclerosis (ALS) at the … Read More
April 14, 2014
(Med Page Today) – Mesenchymal stem cell transplantation is showing promise as a treatment for refractory systemic lupus erythematosus, researchers have reported. In a multicenter study conducted in China that included 40 patients who had persistent disease despite aggressive treatment … Read More
April 11, 2014
(Medical Xpress) – The activity of four transcription factors – proteins that regulate the expression of other genes – appears to distinguish the small proportion of glioblastoma cells responsible for the aggressiveness and treatment resistance of the deadly brain tumor. … Read More
