Whole Genome Sequencing of Babies

March 28, 2018

(Nuffield Council on Bioethics) – Whole genome sequencing of babies explores the ethical issues raised by whole genome sequencing of babies. Whole genome sequencing is cheaper and faster than ever, but interpreting the results is difficult, time-consuming, and expensive. Whole genome sequencing is starting to be used in the NHS to help obtain a diagnosis for some seriously ill babies. What genetic information should be shared with parents, and how genetic data should be stored, accessed, and used requires further public consideration. There is debate about whether genome sequencing could be used to expand NHS newborn screening to include additional genetic conditions.