What the Scientists Who Pioneered Weight-Loss Drugs Want You to Know

June 12, 2023

(Wired) – GLP-1-mimicking drugs seem to be a powerful tool for weight loss: Some people lose 15 percent of their body weight or more after 68 weeks on semaglutide, which is approved in the US for weight loss as Wegovy and for type 2 diabetes under the brand name Ozempic.

But the history of GLP-1 goes back more than 40 years—before obesity became the health crisis it is today. To get a sense of where these drugs came from—and where they might go next—WIRED spoke to two scientists who did some of the earliest work on the GLP-1 hormone, and who have played an important role in the development of these drugs. (Read More)