A Watershed Moment for Cancer Therapies Has Arrived

February 21, 2024

purple cells on a green medium

(Axios) – While CAR-T has been successful in some blood cancers, it’s not yet been approved for solid tumors, which make up about 90% of cancer types. The new therapy class — tumor-infiltrating lymphocytes, or TIL — uses immune cells from a patient’s tumor to mount a long-lasting defense.

Driving the news: The Food and Drug Administration last week gave the first-ever accelerated approval of a TIL to Iovance Biotherapeutics’ melanoma therapy Amtagvi. It was hailed as a major milestone as a growing pipeline of TIL candidates could eventually be deployed against a range of other cancers. (Read More)