Lab-Developed Intestinal Organoids Form Mature Human Tissue in Mice

October 20, 2014

(Eurekalert) – Researchers have successfully transplanted “organoids” of functioning human intestinal tissue grown from pluripotent stem cells in a lab dish into mice – creating an unprecedented model for studying diseases of the intestine. Reporting their results Oct. 19 online in Nature Medicine, scientists from Cincinnati Children’s Hospital Medical Center said that, through additional translational research the findings could eventually lead to bioengineering personalized human intestinal tissue to treat gastrointestinal diseases.