Human Gene Editing Is Controversial. Shoukhrat Mitalipov Isn’t Deterred

April 17, 2019

(Discover Magazine) – Off screen, the sperm vacuum makes a quick pit stop to grab an additional solution before appearing again, poised and ready. In a moment, the egg will be injected not only with sperm but with a dose of CRISPR-Cas9, a DNA editing system that allows scientists to cut out a gene segment and replace it with another. If all goes well, the CRISPR system will cause this single-celled human embryo to repair a disease-causing mutation in its DNA. This lab, at Oregon Health and Science University (OHSU) in Portland, is the only group in the U.S. to publish this kind of research in human embryos.

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