T-Maxxing Has Gone Too Far
January 30, 2026

(The Atlantic) – Whether the goal of these clinics is to treat low T or jack levels up to the max isn’t clear. Many encourage men to aim for excessive T, Michael Irwig, an endocrinologist at Harvard Medical School, told me. A 2022 study of seven direct-to-consumer low-testosterone clinics found that three of them proposed a treatment goal of at least 1,000 nanograms per deciliter—one advertised a goal of 1,500. It should come as no surprise, then, that up to a third of men on TRT don’t have a deficiency, and that the majority of new testosterone users start treatment without completing the blood work needed for a diagnosis. (Read More)