Medicine Is Plagued by Untrustworthy Clinical Trials. How Many Studies Are Faked or Flawed?

July 18, 2023

(Nature) – For more than 150 trials, Carlisle got access to anonymized individual participant data (IPD). By studying the IPD spreadsheets, he judged that 44% of these trials contained at least some flawed data: impossible statistics, incorrect calculations or duplicated numbers or figures, for instance. And 26% of the papers had problems that were so widespread that the trial was impossible to trust, he judged — either because the authors were incompetent, or because they had faked the data. (Read More)