Proteomics and the Future of Embryo Selection

October 15, 2009

With the more widespread availability of assisted reproductive technology services, the incidence of multiple gestations has increased dramatically over the past 2 decades. In vitro fertilization (IVF)-related multiple gestations are responsible for approximately 40% of the increase. Even with more strict transfer policies, 20%-35% of multiple gestations occur after IVF.[1,2] Multiple gestations are associated with many maternal complications (eg, hypertensive complications, diabetes, preterm labor, infectious complications, hemorrhagic complications, operative delivery) and neonatal complications due to prematurity.[3] In addition to the personal and emotional aspects of such outcomes, the effects on the healthcare system due to increased medical expenses also need to be considered. (Medscape)