How some COVID vaccines triggered rare blood-clot disorder

February 12, 2026

vial of Astra Zeneca's covid-19 vaccine

(Nature) – Researchers identify genetic mutation in small group of people who developed the serious disorder after receiving the AstraZeneca or Johnson & Johnson vaccine.

About one in 200,000 people developed vaccine-induced immune thrombocytopenia and thrombosis (VITT), as the syndrome became known, after receiving a vaccine made by Johnson & Johnson in the United States. The rare condition was also reported in about three out of every 100,000 people who received the vaccine made by AstraZeneca in the United Kingdom. Both vaccines used a modified version of an adenovirus, a type of virus known to cause the common cold, to carry the gene for part of the SARS-CoV-2 virus into human cells. This triggered the immune system to create antibodies against SARS-CoV-2. (Read More)