Scientists propose literally channeling stem cell specialization

December 19, 2013

Primary cilia, tiny hair-like structures protruding from a cell, may serve as signaling hubs, influencing a number of biochemical pathways including those involved in stem cell differentiation. Cilia are also sensitive to their surroundings. Working on a hunch that cilia, under the influence of different surface topographies, could alter their signaling patterns, scientists at Queen Mary University of London tried growing mesenchymal stem cells (MSCs) on micro-grooved surfaces. (Genetic Engineering & Biotechnology News)