Scientists Use Haploid Stem Cells to Create an Atlas of the Human Genome

April 25, 2018

(News Medical) – The study, which was conducted by scientists from the Hebrew University of Jerusalem, provides a tool for mapping the role of all human genes. Senior author Nissim Benvenisty and colleagues were able to analyse almost all genes in the human genome by generating more than 180,000 mutations. To generate such a vast amount of mutations, the team combined the CRISPR-Cas9 screening technique with a new form of embryonic cell they had recently isolated.