“Organoids” Reveal How Human Forebrain Develops

January 24, 2020

(Scientific American) – Enter the invention of brain “organoids”: cells grown in 3-D clusters in the lab and designed to mimic the composition of the organ’s tissue. The technology recently reached the point where specific brain regions can be modelled for sufficiently long periods to allow researchers to study their development. Pa?ca and his colleagues have now used organoid models of parts of the human forebrain—the seat of higher cognitive abilities such as complex thought, perception and voluntary movement—to peer into how gene activity drives brain development.