Psilocybin Might Make Your Brain Live in the Moment

September 1, 2026

Swirling colors

(Wired) – Psychedelics are often associated with disconnecting from reality, but a recent neuroimaging study found that psilocybin can actually make our brain activity more attuned to the world around us.

Under the influence of psychedelics, the usual organization of the human brain loosens. That’s what scientists have generally thought, with several studies showing that when we take these substances, the signals pinging between our neurons become more diverse and unpredictable. This increased entropy in our gray matter may underlie the strange, random, and often memorable experiences of psychedelic trips.

But in one of the largest neuroimaging studies on the effects of psilocybin to date, researchers uncovered a hidden order in the apparent chaos. The study, published in Nature, indicates that while psilocybin blurs some of the boundaries within the brain, our neurological reactions to what we’re experiencing in that moment become even more distinct. (Read More)