Pluripotent Cells Created by Nuclear Transfer Can Prompt Immune Reaction, Researchers Find

November 21, 2014

(Medical Xpress) – Mouse cells and tissues created through nuclear transfer can be rejected by the body because of a previously unknown immune response to the cell’s mitochondria, according to a study in mice by researchers at the Stanford University School of Medicine and colleagues in Germany, England and at MIT. The findings reveal a likely, but surmountable, hurdle if such therapies are ever used in humans, the researchers said.