Trial in Africa Probes Antibiotic’s Effects on Child Mortality

August 14, 2019

(The Scientist) – Lietman and his colleagues had that same question in mind when they started the latest trial. At the beginning of the study and six months after the final treatment, they sequenced rectal swabs of 600 children from one to five years old who received four biannual doses of either azithromycin or placebo. All of the children were from Niger, where 10 percent of kids don’t make it to their fifth birthday.  They found a decrease in 35 species of bacteria, including two species of Campylobacter, a genus known to cause diarrhea.